TRANSGENE INACTIVATION - PLANTS FIGHT BACK

被引：345
作者：
FINNEGAN, J
MCELROY, D
机构：
[1] USDA ARS, ALBANY, CA 94710 USA
[2] UNIV CALIF BERKELEY, CTR PLANT GENE EXPRESS, DEPT PLANT BIOL, ALBANY, CA 94710 USA
来源：
BIO-TECHNOLOGY | 1994年 / 12卷 / 09期
关键词：
D O I：
10.1038/nbt0994-883
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Desirable new phenotypes created by the introduction of foreign DNA into plants are frequently unstable following propagation, leading to a loss of the newly acquired traits. This genetic instability is due not to deletion or mutation of the introduced DNA but rather to the inactivation of the transgene. In this review, we discuss the mechanisms that might be responsible for transgene inactivation and examine means of stabilizing gene expression in transgenic plants.
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收藏
页码：883 / 888
页数：6
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