PROTECTION OF PSEUDOMONAS-AERUGINOSA AGAINST CIPROFLOXACIN AND BETA-LACTAMS BY HOMOLOGOUS ALGINATE

被引：49
作者：
HODGES, NA
GORDON, CA
机构：
[1] Pharmaceutical Sci. Res. Group, Department of Pharmacy, Brighton Polytechnic, Moulsecoomb
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1991年 / 35卷 / 11期
关键词：
D O I：
10.1128/AAC.35.11.2450
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Pseudomonas aeruginosa-derived alginate but no other neutral and negatively charged polysaccharides protected mucoid and nonmucoid strains of that organism against ciprofloxacin, gentamicin, ticarcillin, and ceftazidime. Data indicate that alginate has an intrinsic protective effect which is independent of diffusion, charge, or biofilm phenomena.
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页码：2450 / 2452
页数：3
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