BRAIN FACTOR FROM GALLERIA-MELLONELLA (LEPIDOPTERA) STIMULATING SILK GLAND ACTIVITY

被引：5
|
作者：
MICHALIK, J
SZOLAJSKA, E
LASSOTA, Z
机构：
[1] Department of Comparative Biochemistry, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, 02-532
来源：
EXPERIENTIA | 1992年 / 48卷 / 08期
关键词：
NEUROPEPTIDE; SILK GLAND; GALLERIA-MELLONELLA;
D O I：
10.1007/BF02124298
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Brain extracts from day 1-4 last instar larvae of Galleria mellonella (Lepidoptera) stimulate RN synthesis in cultured silk glands from day 3 last instar larvae. When the fibroin-synthesizing posterior parts of silk glands were incubated for 3 h in vitro in the presence of brain extract (0.1 brain equivalent), [H-3]-uridine incorporation into RNA was stimulated more than twofold. The stimulating effect of brain extract showed a dose response relationship. It is suggested that the heat-resistant and protease-sensitive brain factor is a peptide.
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页码：762 / 765
页数：4
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