EFFECT OF DEXTRAN ON THE PLATELET DISTRIBUTION AND LYSABILITY OF EXVIVO THROMBI IN DOGS

被引:8
作者
ABERG, M
BERGENTZ, SE
机构
[1] Department of Plastic Surgery and Experimental Research, University of Lund, Allmanna Sjukhuset, Malmo
关键词
Dextran; Lysability; LysabilityKey Words. Dextran; Platelets Thrombi;
D O I
10.1159/000128076
中图分类号
R61 [外科手术学];
学科分类号
摘要
Dextran infusion causes an increased lysability of ex vivo thrombi. This increased lysability is shown to be accompanied by a change in the distribution of51Cr-labelled platelets. Rather than being localized to the head of the thrombus, after dextran infusion the platelets are found to be more evenly distributed. This change in platelet distribution is secondary to an effect of dextran on platelet function, probably via previously demonstrated impairment of the function of factor VIII. It is suggested that the increase in thrombus lysability is due to the change in platelet function. © 1979 S. Karger AG, Basel.
引用
收藏
页码:282 / 288
页数:7
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