CHOLESTEROL-CONTAINING NONIONIC AMPHIPHILIC POLYMERS - SYNTHESIS AND SOLUBILIZATION OF CHOLESTEROL

被引：5
|
作者：
CHO, I [1 ]
JEONG, SW [1 ]
机构：
[1] KOREA ADV INST SCI & TECHNOL, DEPT CHEM, TAEJON 305701, SOUTH KOREA
来源：
MACROMOLECULAR CHEMISTRY AND PHYSICS | 1995年 / 196卷 / 03期
关键词：
D O I：
10.1002/macp.1995.021960315
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Solubilization of cholesterol in water with cholesterol-containing poly(N-vinyl-2-pyrrolidone) was studied. The non-ionic amphiphilic polymers were synthesized via copolymerization of cholesterol-based monomers with N-vinyl-2-pyrrolidone; the copolymers were dissolved isotropically in water to form hydrophobic microdomains solubilizing cholesterol efficiently. Electron micrographs revealed that the amphiphilic polymers undergo aggregational changes from random microphases to bilayers as free cholesterol is incorporated into the polymeric hydrophobic domains.
引用
收藏
页码：869 / 875
页数：7
相关论文
共 50 条
  • [41] Membrane Interaction of Ibuprofen with Cholesterol-Containing Lipid Membranes
    Kremkow, Jan
    Luck, Meike
    Huster, Daniel
    Mueller, Peter
    Scheidt, Holger A.
    BIOMOLECULES, 2020, 10 (10) : 1 - 12
  • [42] Charge-Convertible and Reduction-Sensitive Cholesterol-Containing Amphiphilic Copolymers for Improved Doxorubicin Delivery
    Wang, Zhao
    Guo, Xinyu
    Hao, Lingyun
    Zhang, Xiaojuan
    Lin, Qing
    Sheng, Ruilong
    MATERIALS, 2022, 15 (18)
  • [43] Entropic repulsion of cholesterol-containing layers counteracts bioadhesion
    Friedrichs, Jens
    Helbig, Ralf
    Hilsenbeck, Julia
    Pandey, Prithvi Raj
    Sommer, Jens-Uwe
    Renner, Lars David
    Pompe, Tilo
    Werner, Carsten
    NATURE, 2023, 618 (7966) : 733 - +
  • [44] ROENTGENOGRAM OF MONTH - CALCIFIED CHOLESTEROL-CONTAINING PLEURAL EFFUSION
    LAGUARDA, R
    BENNER, MH
    SNIDER, GL
    CHEST, 1971, 60 (06) : 597 - &
  • [45] INTRA-MOLECULAR ORDERING OF CHOLESTEROL-CONTAINING COPOLYMERS
    BORISOVA, TI
    BURSHTEIN, LL
    STEPANOVA, TP
    FREIDZON, YS
    SHIBAEV, VP
    VYSOKOMOLEKULYARNYE SOEDINENIYA SERIYA A, 1978, 20 (06): : 1380 - 1384
  • [46] Structure and physical properties of comblike polymers and The structure and properties of liquid-crystalline cholesterol-containing polymers - Comment
    Shibaev, VP
    VYSOKOMOLEKULYARNYE SOEDINENIYA SERIYA A & SERIYA B, 1999, 41 (12): : 2024 - 2025
  • [47] ROLE OF INTRAMOLECULAR STRUCTURE FORMATION IN REALIZATION OF LIQUID-CRYSTAL STATE OF CHOLESTEROL-CONTAINING POLYMERS
    SHIBAEV, VP
    FREIDZON, JS
    AGRANOVICH, IM
    PAUTOV, VD
    ANUFRIEVA, EV
    PLATE, NA
    DOKLADY AKADEMII NAUK SSSR, 1977, 232 (02): : 401 - 404
  • [48] X-RAY STRUCTURAL INVESTIGATIONS OF SOME LIQUID-CRYSTAL CHOLESTEROL-CONTAINING POLYMERS
    GUDKOV, VA
    CHISTYAKOV, IG
    KRISTALLOGRAFIYA, 1982, 27 (01): : 160 - &
  • [49] LIQUID-CRYSTALLINE STATE OF CHOLESTEROL-CONTAINING MONOMERS
    FREIDZON, YS
    KHARITONOV, AV
    SHIBAEV, VP
    PLATE, NA
    MOLECULAR CRYSTALS AND LIQUID CRYSTALS, 1982, 88 (1-4): : 87 - 97
  • [50] Sphingolipid partitioning into ordered domains in cholesterol-free and cholesterol-containing lipid bilayers
    Wang, TY
    Silvius, JR
    BIOPHYSICAL JOURNAL, 2003, 84 (01) : 367 - 378
12345