FORENSIC INVESTIGATION OF GENTAMICIN SULFATES BY ANION-EXCHANGE ION CHROMATOGRAPHY WITH PULSED ELECTROCHEMICAL DETECTION

Many methods exist for the separation of gentamicin C complex components, C-1, C-1a, C-2 and C-2a. In an investigation of possible counterfeit suppliers of gentamicin sulfate, a new method utilized high-pH anion-exchange separation on a carbohydrate column, with pulsed electrochemical detection on a gold electrode. Component ratios and the presence and/or absence of additional peaks were used to link or dissociate forensic samples.