The Role of Ursodeoxycholic Acid in Acute Viral Hepatitis: an Evidence-based Case Report

被引:0
作者
Wijaya, Indra [1 ]
机构
[1] Univ Pelita Harapan, Dept Internal Med, Fac Med, Jl Blvd Palem Raya, Kec Tangerang 15811, Banten, Indonesia
关键词
ursodeoxycholic acid; acute viral hepatitis;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aim: to review the role of ursodeoxycholic acid in acute viral hepatitis. Methods: following literature searching according to the clinical question on Pubmed and Cochrane Library. After filtered with our inclusion and exclusion criteria, one meta-analysis and two randomized clinical trials are obtained. Through critical appraisal, it was concluded that the articles meet the criteria for validity and relevance. Results: the article found that there is a positive effect of ursodeoxycholic acid on the activity of serum transaminases and cholestasis indexes. However, there is insufficient evidence to support or to refute effects of ursodeoxycholic acid on disease's course as well as the viral load. Conclusion: better method of clinical trials are needed to obtain a valid and applicable result for daily practice.
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页码:352 / 357
页数:6
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