ISOTACHOPHORESIS WITH ELECTROOSMOTIC FLOW - OPEN VERSUS CLOSED SYSTEMS

If isotachophoretic (ITP) experiments are carried out in open systems, an electroosmotic flow (EOF) will act on the ITP system. In ITP experiments with EOF in open systems four modes can be distinguished, viz, anionic, cationic, reversed anionic and reversed cationic modes. The applicability of these modes depends strongly on the velocity of the EOF. Examples of separations are given showing some typical features of these modes. Detailed consideration of a mathematical model for ITP with EOF showed that this model is identical with that of ITP without EOF.