THE CANNABINOID RECEPTOR - BIOCHEMICAL, ANATOMICAL AND BEHAVIORAL CHARACTERIZATION

被引：282

作者：

HOWLETT, AC

BIDAUTRUSSELL, M

DEVANE, WA

MELVIN, LS

JOHNSON, MR

HERKENHAM, M

机构：

[1] PFIZER INC,CENT RES,GROTON,CT 06340

[2] NIMH,FUNCT NEUROANAT UNIT,BETHESDA,MD 20892

来源：

TRENDS IN NEUROSCIENCES | 1990年 / 13卷 / 10期

关键词：

D O I：

10.1016/0166-2236(90)90124-S

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The actions of the active principle of marihuana, Δ9-tetrahydrocannabinol, are mimicked by synthetic cannabinoid agonists showing high potency and enantioselectivity in behavioral assays. These drugs have been used to characterize cannabinoid receptor binding, biochemistry and pharmacology, leading to a better understanding of the effects of cannabinoids in the CNS of humans and experimental animals. © 1990.

引用

页码：420 / 423

页数：4

共 42 条

[1] INHIBITION OF NALOXONE-INDUCED WITHDRAWAL IN MORPHINE-DEPENDENT MICE BY "L-TRANS-DELTA9-TETRAHYDROCANNABINOL [J].