A Case of Immunotactoid Glomerulopathy in a Patient with Multiple Myeloma

被引：0

作者：

Rekhtina, Irina G. ^{[1
]}

Mendeleeva, Larisa P. ^{[2
]}

Povivaitite, Patricia E. ^{[3
]}

机构：

[1] Minist Healthcare Russian Federat, Natl Res Ctr Hematol, Dept Nephrol, Novi Zikovski Pr 4, Moscow 125167, Russia

[2] Minist Healthcare Russian Federat, Natl Res Ctr Hematol, Dept High Dose Chemotherapy Paraproteinem Hemobla, Moscow, Russia

[3] Reg Bur Pathol, Dept Pathol, Rostov Na Donu, Russia

来源：

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH | 2018年 / 12卷 / 01期

关键词：

Glomerular infiltration; Glomerulonephritis; Microtubules;

D O I：

10.7860/JCDR/2018/24366.11073

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cases of Immunotactoid Glomerulopathy (ITG) in patients with Multiple Myeloma (MM) are extremely rare. Consequently, data on efficacy and therapy results are limited. We report on a rare case of long-term follow up patient with MM and ITG. After chemotherapy the patient achieved complete remission with complete recovery of renal function. A repeat renal biopsy revealed complete resorption of the deposits. After four years, ITG was diagnosed again in another kidney biopsy during a relapse of MM. There was excessive glomerular infiltration by lymphoid cells and obstruction of capillary lumen was identified. Bundles of microtubules, similar to the deposits in kidneys, were revealed in some lymphoid cells.

引用

页码：OD12 / OD13

页数：2

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