Field cancerization of oral cavity - A case series with review of literature

被引:0
作者
Rema, Jayalekshmy [1 ]
Shilpa, Padar Shastry [1 ]
Balan, Anita [2 ]
Ramnarayan, Belur Krishnaprasad [3 ]
Maligi, Prathima [4 ]
机构
[1] Vydehi Inst Dent Sci & Res Ctr, Bangalore, Karnataka, India
[2] Govt Dent Coll, Calicut, Kerala, India
[3] Dayananda Sagar Coll Dent Sci, Bangalore, Karnataka, India
[4] Bangalore Inst Dent Sci, Bangalore, Karnataka, India
关键词
Oral cancer; Field cancerization; Head and neck squamous cell carcinoma;
D O I
10.1016/j.ajoms.2015.05.008
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
The concept of field cancerisation was proposed by Slaughter et al. in 1953. Field cancerization of the mucosa of aerodigestive tract frequently develops on account of tobacco and alcohol usage. It is characterized by a variety of premalignant and malignant epithelial changes that may lead to the development of multiple primary cancers of the aerodigestive tract. Presence of multiple primary tumors may adversely affect the diagnosis and treatment of the oral cancer. This article highlights an update and a case series of oral field cancerization, considering the carcinogenetic influence of tobacco and alcohol in the development of multiple primary tumors of the oral cavity. (C) 2015 Asian AOMS, ASOMP, JSOP, JSOMS, JSOM, and JAMI. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:867 / 875
页数:9
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