CYCLOSPORINE-A IN A PREGNANT PATIENT AFFECTED WITH SYSTEMIC LUPUS-ERYTHEMATOSUS

被引：15

作者：

DORIA, A ^{[1
]}

DILENARDO, L ^{[1
]}

VARIO, S ^{[1
]}

CALLIGARO, A ^{[1
]}

VACCARO, E ^{[1
]}

GAMBARI, PF ^{[1
]}

机构：

[1] UNIV PADUA,DEPT OBSTET & GYNECOL,I-35128 PADUA,ITALY

来源：

RHEUMATOLOGY INTERNATIONAL | 1992年 / 12卷 / 02期

关键词：

CYCLOSPORINE-A; PREGNANCY; SYSTEMIC LUPUS ERYTHEMATOSUS; CONNECTIVE TISSUE DISEASES;

D O I：

10.1007/BF00300981

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Few data regarding the use of cyclosporin A (CyA) in pregnancy are available and those available refer mainly to transplant recipients and not to patients with connective tissue diseases. We report the case of a patient with systemic lupus erythematosus (SLE), taking CyA before, during and after her pregnancy at a dose of 4 mg/kg per day. CyA was effective in controlling SLE activity and no side effects were observed in mother or baby. The lack of teratogenicity in this case was in keeping with previous reports in experimental systems, animals and human transplant recipients. If our observation is confirmed by further studies, CyA might become useful in the treatment of pregnant patients with SLE.

引用

页码：77 / 78

页数：2

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