A Meta-analysis and Systematic Review of Randomised Controlled Trials Comparing Cognitive Behavioural Therapy to Conventional Treatment of Osteoarthritis
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作者:
McMahon, Samuel E.
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Frere Hosp, Dept Trauma & Orthopaed, East London, Eastern Cape, South AfricaFrere Hosp, Dept Trauma & Orthopaed, East London, Eastern Cape, South Africa
McMahon, Samuel E.
[1
]
Smith, Toby O.
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Univ East Anglia, Fac Med & Hlth Sci, Norwich NR4 7TJ, Norfolk, EnglandFrere Hosp, Dept Trauma & Orthopaed, East London, Eastern Cape, South Africa
Smith, Toby O.
[2
]
Raju, Karthickeyan
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Royal Surrey Hosp, Guildford, Surrey, EnglandFrere Hosp, Dept Trauma & Orthopaed, East London, Eastern Cape, South Africa
Raju, Karthickeyan
[3
]
Hing, Caroline B.
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St George Hosp, Dept Trauma & Orthopaed, London SW17 0QT, EnglandFrere Hosp, Dept Trauma & Orthopaed, East London, Eastern Cape, South Africa
Hing, Caroline B.
[4
]
机构:
[1] Frere Hosp, Dept Trauma & Orthopaed, East London, Eastern Cape, South Africa
[2] Univ East Anglia, Fac Med & Hlth Sci, Norwich NR4 7TJ, Norfolk, England
[3] Royal Surrey Hosp, Guildford, Surrey, England
[4] St George Hosp, Dept Trauma & Orthopaed, London SW17 0QT, England
Objectives: To identify whether cognitive behavioural therapy (CBT) is effective in the management of osteoarthritis (OA). Methods: A mixed meta-analysis and narrative review of the literature was conducted. Three hundred and eighty five studies were identified by literature search, five of which were included for review. The included studies were randomised controlled trials (RCT) that compared CBT to conventional therapy. Results: On analysis, meta-analysis of the primary outcome, pain, revealed a statistically significant improvement in symptoms (p<0.05) between those who received CBT versus conventional management. Narrative review revealed varying results from no change in pain to significant improvements. A meta-analysis was also performed to assess 'other symptoms'. This demonstrated no significant difference between the groups (p>0.05). Narrative review of patient function revealed a trend of no clinical benefit (p>0.05). Anxiety and depression scores were more positive for those who received CBT compared to conventional therapy, with significant improvement seen in the short-term (p<0.05). Conclusions: The role of CBT in the management of OA remains equivocal. Some encouraging results were seen with regard to pain, anxiety and depression. We believe further high quality RCTs are necessary to adequately answer the study question.
机构:
Univ London Imperial Coll Sci Technol & Med, London SW7 2AZ, England
Hawkes Bay DHB, Napier, New Zealand
Univ Otago, Wellington Sch Med, Wellington, New ZealandUniv London Imperial Coll Sci Technol & Med, London SW7 2AZ, England
Newton-Howes, Giles
Wood, Rebecca
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Univ London Imperial Coll Sci Technol & Med, London SW7 2AZ, EnglandUniv London Imperial Coll Sci Technol & Med, London SW7 2AZ, England
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Western Univ, Schulich Sch Med & Dent, London, ON, CanadaWestern Univ, Schulich Sch Med & Dent, London, ON, Canada
Alphonsus, Lotus
De Silva, Theshani A.
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Western Univ, Schulich Sch Med & Dent, London, ON, CanadaWestern Univ, Schulich Sch Med & Dent, London, ON, Canada
De Silva, Theshani A.
Ma, Christopher
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Alimentiv Inc, London, ON, Canada
Univ Calgary, Dept Med, Div Gastroenterol & Hepatol, Calgary, AB, Canada
Univ Calgary, Cumming Sch Med, Dept Community Hlth Sci, Calgary, AB, CanadaWestern Univ, Schulich Sch Med & Dent, London, ON, Canada
Ma, Christopher
MacDonald, John K.
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Alimentiv Inc, London, ON, CanadaWestern Univ, Schulich Sch Med & Dent, London, ON, Canada
MacDonald, John K.
Hanzel, Jurij
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Alimentiv Inc, London, ON, Canada
Univ Ljubljana, Univ Med Ctr Ljubljana, Fac Med, Dept Gastroenterol, Ljubljana, SloveniaWestern Univ, Schulich Sch Med & Dent, London, ON, Canada
Hanzel, Jurij
Beaton, Melanie
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Western Univ, Schulich Sch Med & Dent, London, ON, Canada
Western Univ, Dept Med, Div Gastroenterol, London, ON, CanadaWestern Univ, Schulich Sch Med & Dent, London, ON, Canada
Beaton, Melanie
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Bessissow, Talat
Kayal, Maia
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Icahn Sch Med Mt Sinai, Dept Med, Div Gastroenterol, New York, NY USAWestern Univ, Schulich Sch Med & Dent, London, ON, Canada
Kayal, Maia
Sedano, Rocio
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机构:
Alimentiv Inc, London, ON, Canada
Western Univ, Dept Med, Div Gastroenterol, London, ON, CanadaWestern Univ, Schulich Sch Med & Dent, London, ON, Canada
Sedano, Rocio
Singh, Siddharth
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Univ Calif San Diego, Dept Med, Div Gastroenterol, San Diego, CA USAWestern Univ, Schulich Sch Med & Dent, London, ON, Canada
Singh, Siddharth
Jairath, Vipul
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Alimentiv Inc, London, ON, Canada
Western Univ, Dept Med, Div Gastroenterol, London, ON, Canada
Western Univ, Dept Epidemiol & Biostat, London, ON, Canada
Lawson Hlth Res Inst, London, ON, Canada
Biostat Western Univ, Dept Med, Dept Epidemiol, Div Gastroenterol, London, ON, CanadaWestern Univ, Schulich Sch Med & Dent, London, ON, Canada
机构:
Yonsei Univ, Severance Cardiovasc Hosp, Dept Pediat, Div Pediat Cardiol,Coll Med, Seoul, South Korea
Yonsei Univ, Dept Pediat, Coll Med, Seoul, South KoreaYonsei Univ, Severance Cardiovasc Hosp, Dept Pediat, Div Pediat Cardiol,Coll Med, Seoul, South Korea
Kim, A. Y.
Woo, W.
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Yonsei Univ, Gangnam Severance Hosp, Dept Thorac & Cardiovasc Surg, Coll Med, Seoul, South KoreaYonsei Univ, Severance Cardiovasc Hosp, Dept Pediat, Div Pediat Cardiol,Coll Med, Seoul, South Korea
Woo, W.
Saxena, A.
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All India Inst Med Sci, Dept Cardiol, New Delhi, IndiaYonsei Univ, Severance Cardiovasc Hosp, Dept Pediat, Div Pediat Cardiol,Coll Med, Seoul, South Korea
Saxena, A.
Tanidir, I. C.
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Basaksehir Cam & Sakura City Hosp, Dept Pediat Cardiol, Istanbul, TurkiyeYonsei Univ, Severance Cardiovasc Hosp, Dept Pediat, Div Pediat Cardiol,Coll Med, Seoul, South Korea
Tanidir, I. C.
Yao, A.
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Univ Tokyo, Dept Hlth Serv Promot, Tokyo, JapanYonsei Univ, Severance Cardiovasc Hosp, Dept Pediat, Div Pediat Cardiol,Coll Med, Seoul, South Korea
Yao, A.
Kurniawati, Y.
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Natl Cardiovasc Ctr Harapan Kita, Dept Pediat Cardiol, Jakarta, IndonesiaYonsei Univ, Severance Cardiovasc Hosp, Dept Pediat, Div Pediat Cardiol,Coll Med, Seoul, South Korea
Kurniawati, Y.
Thakur, V.
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Univ Toronto, Hosp Sick Children, Labatt Family Heart Ctr, Dept Pediat, Toronto, ON, CanadaYonsei Univ, Severance Cardiovasc Hosp, Dept Pediat, Div Pediat Cardiol,Coll Med, Seoul, South Korea
Thakur, V.
Shin, Y. R.
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Yonsei Univ, Dept Cardiovasc Surg, Coll Med, Seoul, South KoreaYonsei Univ, Severance Cardiovasc Hosp, Dept Pediat, Div Pediat Cardiol,Coll Med, Seoul, South Korea
Shin, Y. R.
Shin, J. I.
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Univ Toronto, Hosp Sick Children, Labatt Family Heart Ctr, Dept Pediat, Toronto, ON, Canada
Yonsei Univ, Inst Convergence Sci, Severance Underwood Meta Res Ctr, Seoul, South KoreaYonsei Univ, Severance Cardiovasc Hosp, Dept Pediat, Div Pediat Cardiol,Coll Med, Seoul, South Korea
Shin, J. I.
Jung, J. W.
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Yonsei Univ, Severance Cardiovasc Hosp, Dept Pediat, Div Pediat Cardiol,Coll Med, Seoul, South Korea
Yonsei Univ, Dept Pediat, Coll Med, Seoul, South KoreaYonsei Univ, Severance Cardiovasc Hosp, Dept Pediat, Div Pediat Cardiol,Coll Med, Seoul, South Korea
Jung, J. W.
Barron, D. J.
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Univ Toronto, Hosp Sick Children, Dept Surg, Div Cardiovasc Surg, Toronto, ON, CanadaYonsei Univ, Severance Cardiovasc Hosp, Dept Pediat, Div Pediat Cardiol,Coll Med, Seoul, South Korea
Barron, D. J.
Int HLHS Res Network Collaborators
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机构:Yonsei Univ, Severance Cardiovasc Hosp, Dept Pediat, Div Pediat Cardiol,Coll Med, Seoul, South Korea
机构:
Beijing Univ Chinese Med, Ctr Evidence Based Chinese Med, 11 Bei San Huan Dong Lu, Beijing 100029, Peoples R ChinaBeijing Univ Chinese Med, Ctr Evidence Based Chinese Med, 11 Bei San Huan Dong Lu, Beijing 100029, Peoples R China
Zhang, Ying
Yang, Xue
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Heilongjiang Univ Tradit Chinese Med, Affiliated Hosp 1, Haerbin 150000, Peoples R ChinaBeijing Univ Chinese Med, Ctr Evidence Based Chinese Med, 11 Bei San Huan Dong Lu, Beijing 100029, Peoples R China
Yang, Xue
Jia, Li-Yan
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Beijing Univ Chinese Med, Ctr Evidence Based Chinese Med, 11 Bei San Huan Dong Lu, Beijing 100029, Peoples R ChinaBeijing Univ Chinese Med, Ctr Evidence Based Chinese Med, 11 Bei San Huan Dong Lu, Beijing 100029, Peoples R China
Jia, Li-Yan
Liu, Bao-Li
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Beijing Hosp Tradit Chinese Med, Dept Nephrol, Beijing 100029, Peoples R ChinaBeijing Univ Chinese Med, Ctr Evidence Based Chinese Med, 11 Bei San Huan Dong Lu, Beijing 100029, Peoples R China
Liu, Bao-Li
Zhang, Sheng-Rong
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Beijing Hosp Tradit Chinese Med, Dept Nephrol, Beijing 100029, Peoples R ChinaBeijing Univ Chinese Med, Ctr Evidence Based Chinese Med, 11 Bei San Huan Dong Lu, Beijing 100029, Peoples R China
Zhang, Sheng-Rong
Wang, Gui-Yuan
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Heilongjiang Univ Tradit Chinese Med, Affiliated Hosp 1, Haerbin 150000, Peoples R ChinaBeijing Univ Chinese Med, Ctr Evidence Based Chinese Med, 11 Bei San Huan Dong Lu, Beijing 100029, Peoples R China
Wang, Gui-Yuan
Wang, Ling-Shu
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Heilongjiang Univ Tradit Chinese Med, Affiliated Hosp 1, Haerbin 150000, Peoples R ChinaBeijing Univ Chinese Med, Ctr Evidence Based Chinese Med, 11 Bei San Huan Dong Lu, Beijing 100029, Peoples R China
Wang, Ling-Shu
Liu, Jian-Ping
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Beijing Univ Chinese Med, Ctr Evidence Based Chinese Med, 11 Bei San Huan Dong Lu, Beijing 100029, Peoples R ChinaBeijing Univ Chinese Med, Ctr Evidence Based Chinese Med, 11 Bei San Huan Dong Lu, Beijing 100029, Peoples R China