INACTIVATION OF CARBOXYPEPTIDASE-Y BY MUTATIONAL REMOVAL OF THE PUTATIVE ESSENTIAL HISTIDYL RESIDUE

被引：23
作者：
BECH, LM
BREDDAM, K
机构：
来源：
CARLSBERG RESEARCH COMMUNICATIONS | 1989年 / 54卷 / 05期
关键词：
D O I：
10.1007/BF02904470
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：165 / 171
页数：7
相关论文
共 36 条
[1]  
BAI Y, 1979, J BIOL CHEM, V254, P8473
[2]  
BAUDYS M, 1983, INT J PEPT PROT RES, V22, P66
[3]   3-DIMENSIONAL STRUCTURE OF PROTEINASE-K AT 0.15-NM RESOLUTION [J].
BETZEL, C ;
PAL, GP ;
SAENGER, W .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1988, 178 (01) :155-171
[4]   ACTIVE-SITE GEOMETRY OF PROTEINASE-K - CRYSTALLOGRAPHIC STUDY OF ITS COMPLEX WITH A DIPEPTIDE CHLOROMETHYL KETONE INHIBITOR [J].
BETZEL, C ;
PAL, GP ;
STRUCK, M ;
JANY, KD ;
SAENGER, W .
FEBS LETTERS, 1986, 197 (1-2) :105-110
[5]   CYANYLATION OF THE SINGLE SULFHYDRYL-GROUP IN CARBOXYPEPTIDASE-Y WITH CYANOGEN-BROMIDE [J].
BREDDAM, K ;
KANSTRUP, A .
CARLSBERG RESEARCH COMMUNICATIONS, 1987, 52 (01) :65-71
[6]   IDENTIFICATION OF METHIONYL AND CYSTEINYL RESIDUES IN THE SUBSTRATE BINDING-SITE OF CARBOXYPEPTIDASE-Y [J].
BREDDAM, K ;
SVENDSEN, I .
CARLSBERG RESEARCH COMMUNICATIONS, 1984, 49 (07) :639-645
[7]   MODIFICATION OF THE SINGLE SULFHYDRYL-GROUP OF CARBOXYPEPTIDASE-Y WITH MERCURIALS - INFLUENCE ON ENZYME SPECIFICITY [J].
BREDDAM, K .
CARLSBERG RESEARCH COMMUNICATIONS, 1983, 48 (01) :9-19
[8]   CHEMICALLY MODIFIED CARBOXYPEPTIDASE-Y WITH INCREASED AMIDASE ACTIVITY [J].
BREDDAM, K .
CARLSBERG RESEARCH COMMUNICATIONS, 1984, 49 (05) :535-554
[9]   PRIMARY STRUCTURE AND ENZYMATIC-PROPERTIES OF CARBOXYPEPTIDASE-II FROM WHEAT BRAN [J].
BREDDAM, K ;
SORENSEN, SB ;
SVENDSEN, I .
CARLSBERG RESEARCH COMMUNICATIONS, 1987, 52 (04) :297-311
[10]   SERINE CARBOXYPEPTIDASES - A REVIEW [J].
BREDDAM, K .
CARLSBERG RESEARCH COMMUNICATIONS, 1986, 51 (02) :83-128
1234