THE EFFECT OF COMPACTIN, A POTENT INHIBITOR OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME-A REDUCTASE-ACTIVITY, ON CHOLESTEROGENESIS AND SERUM-CHOLESTEROL LEVELS IN RATS AND CHICKS

被引：72
作者：
FEARS, R
RICHARDS, DH
FERRES, H
机构：
来源：
ATHEROSCLEROSIS | 1980年 / 35卷 / 04期
关键词：
D O I：
10.1016/0021-9150(80)90185-9
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：439 / 449
页数：11
相关论文
共 25 条
[1]  
BARTLETT GR, 1959, J BIOL CHEM, V234, P466
[2]   LACK OF CORRELATION BETWEEN RATE OF CHOLESTEROL-BIOSYNTHESIS AND ACTIVITY OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME-A REDUCTASE IN RATS AND IN FIBROBLASTS TREATED WITH ML-236B [J].
BENSCH, WR ;
INGEBRITSEN, TS ;
DILLER, ER .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1978, 82 (01) :247-254
[3]  
BETTERIDGE DJ, 1978, LANCET, V2, P1342
[4]   CRYSTAL AND MOLECULAR-STRUCTURE OF COMPACTIN, A NEW ANTIFUNGAL METABOLITE FROM PENICILLIUM-BREVICOMPACTUM [J].
BROWN, AG ;
SMALE, TC ;
KING, TJ ;
HASENKAMP, R ;
THOMPSON, RH .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1976, (11) :1165-1173
[5]  
BROWN MS, 1978, J BIOL CHEM, V253, P1121
[6]  
BURSTEIN M, 1973, ADV LIPID RES, V11, P68
[7]   COMPETITIVE INHIBITION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE BY ML-236A AND ML-236B FUNGAL METABOLITES, HAVING HYPOCHOLESTEROLEMIC ACTIVITY [J].
ENDO, A ;
KURODA, M ;
TANZAWA, K .
FEBS LETTERS, 1976, 72 (02) :323-326
[8]   ML-236A, ML-236B, AND ML-236C, NEW INHIBITORS OF CHOLESTEROGENESIS PRODUCED BY PENICILLIUM CITRINUM [J].
ENDO, A ;
KURODA, M ;
TSUJITA, Y .
JOURNAL OF ANTIBIOTICS, 1976, 29 (12) :1346-1348
[9]   INHIBITION OF CHOLESTEROL-SYNTHESIS INVITRO AND INVIVO BY ML-236A AND ML-236B, COMPETITIVE INHIBITORS OF 3-HYDROXY-3-METHYLGLUTARYL-COENZYME-A REDUCTASE [J].
ENDO, A ;
TSUJITA, Y ;
KURODA, M ;
TANZAWA, K .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1977, 77 (01) :31-36
[10]  
EVRARD E, 1968, J LIPID RES, V9, P226
123