FUNCTIONALIZATION OF TECHNETIUM COMPLEXES TO MAKE THEM ACTIVE IN-VIVO

被引：20

作者：

SPIES, H

JOHANNSEN, B

机构：

来源：

ANALYST | 1995年 / 120卷 / 03期

关键词：

RADIOTRACERS; TECHNETIUM; RHENIUM; FUNCTIONALIZED COMPLEX;

D O I：

10.1039/an9952000775

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

In order to obtain efficient access to novel technetium and rhenium complexes in radiotracer design, the principle of preparing mixed-ligand complexes in which small-sized chelate units are bound to biologically relevant substituents was applied to thioglucose and thiocholesterol as substituents. Complexes of rhenium(v) of the formula [ReO(SSS)(SR)] (HSSSH = tridentate dithiol HSCH2CH2SCH2CH2SH; RSH = 1-thio-beta-D-glucose and cholest-5-en-3 beta-thiol) were prepared and structurally characterized.

引用

页码：775 / 777

页数：3