FUNCTIONALIZATION OF TECHNETIUM COMPLEXES TO MAKE THEM ACTIVE IN-VIVO

被引：20
作者：
SPIES, H
JOHANNSEN, B
机构：
来源：
ANALYST | 1995年 / 120卷 / 03期
关键词：
RADIOTRACERS; TECHNETIUM; RHENIUM; FUNCTIONALIZED COMPLEX;
D O I：
10.1039/an9952000775
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
In order to obtain efficient access to novel technetium and rhenium complexes in radiotracer design, the principle of preparing mixed-ligand complexes in which small-sized chelate units are bound to biologically relevant substituents was applied to thioglucose and thiocholesterol as substituents. Complexes of rhenium(v) of the formula [ReO(SSS)(SR)] (HSSSH = tridentate dithiol HSCH2CH2SCH2CH2SH; RSH = 1-thio-beta-D-glucose and cholest-5-en-3 beta-thiol) were prepared and structurally characterized.
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收藏
页码：775 / 777
页数：3
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