HEMATOLOGICAL-CHANGES PRODUCED IN MICE BY OCHRATOXIN-A

被引：21
作者：
GUPTA, M
BANDOPADHYAY, S
PAUL, B
MAJUMDER, SK
机构：
[1] Division of Pharmacology, Department of Pharmacy, Jadavpur University, Calcultta
来源：
TOXICOLOGY | 1979年 / 14卷 / 01期
关键词：
D O I：
10.1016/0300-483X(79)90095-7
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The effects of ochratoxin A (5 mg/kg, intraperitoneal) on clotting time, hemoglobin, total count of red blood cells and white blood cells and differential count of white blood cells were studied in mice. This mycotoxin caused a significant decrease in the hemaglobin level and in the total count of red blood cells. Among white blood cells there was a significant increase in small lymphocytes and a significant fall in the count of neutrophils, basophils and monocytes in treated mice. The administration of ochratoxin A also prolonged the clotting time by more than 6-fold. © 1979.
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页码：95 / 98
页数：4
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