Fluorine-18 patents (2009-2015). Part 2: new radiochemistry

被引：11

作者：

Mossine, Andrew V. ^{[1
]}

Thompson, Stephen ^{[1
]}

Brooks, Allen F. ^{[1
]}

Sowa, Alexandra R. ^{[2
]}

Miller, Jason M. ^{[2
]}

Scott, Peter J. H. ^{[1
,2
]}

机构：

[1] Univ Michigan, Dept Radiol, Sch Med, 1301 Catherine St, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Dept Med Chem, 428 Church St, Ann Arbor, MI 48109 USA

来源：

PHARMACEUTICAL PATENT ANALYST | 2016年 / 5卷 / 05期

关键词：

F-18; fluorine-18; PET radiotracers; positron emission tomography; radiochemistry;

D O I：

10.4155/ppa-2016-0028

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Fluorine-18 (F-18) is one of the most common positron-emitting radionuclides used in the synthesis of positron emission tomography radiotracers due to its ready availability, convenient half-life and outstanding imaging properties. In Part 1 of this review, we presented the first analysis of patents issued for novel radiotracers labeled with fluorine-18. In Part 2, we follow-up with a focus on patents issued for new radiochemistry methodology using fluorine-18 issued between January 2009 and December 2015.

引用

页码：319 / 349

页数：31

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