Fluorine-18 patents (2009-2015). Part 2: new radiochemistry

被引：11
|
作者：
Mossine, Andrew V. [1 ]
Thompson, Stephen [1 ]
Brooks, Allen F. [1 ]
Sowa, Alexandra R. [2 ]
Miller, Jason M. [2 ]
Scott, Peter J. H. [1 ,2 ]
机构：
[1] Univ Michigan, Dept Radiol, Sch Med, 1301 Catherine St, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Dept Med Chem, 428 Church St, Ann Arbor, MI 48109 USA
来源：
PHARMACEUTICAL PATENT ANALYST | 2016年 / 5卷 / 05期
关键词：
F-18; fluorine-18; PET radiotracers; positron emission tomography; radiochemistry;
D O I：
10.4155/ppa-2016-0028
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Fluorine-18 (F-18) is one of the most common positron-emitting radionuclides used in the synthesis of positron emission tomography radiotracers due to its ready availability, convenient half-life and outstanding imaging properties. In Part 1 of this review, we presented the first analysis of patents issued for novel radiotracers labeled with fluorine-18. In Part 2, we follow-up with a focus on patents issued for new radiochemistry methodology using fluorine-18 issued between January 2009 and December 2015.
引用
收藏
页码：319 / 349
页数：31
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