DARK-ADAPTATION IN PATIENTS WITH BEST VITELLIFORM MACULAR DYSTROPHY

被引:5
作者
BACA, W [1 ]
FISHMAN, GA [1 ]
ALEXANDER, KR [1 ]
GLENN, AM [1 ]
机构
[1] UNIV ILLINOIS,COLL MED,CTR EYE,DEPT OPHTHALMOL & VISUAL SCI,CHICAGO,IL 60612
关键词
D O I
10.1136/bjo.78.6.430
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Psychophysical dark adaptation studies were performed in six patients with Best vitelliform macular dystrophy (BVMD) using a Goldmann-Weekers dark adaptometer. Prebleach thresholds were determined before obtaining a postbleach full recovery curve. Unlike patients with Stargardt macular dystrophy, all patients with BVMD showed a normal time to reach their baseline dark adapted thresholds after bleaching of their rod visual pigment when tested in clinically normal appearing retina. Although a lipofuscin material accumulates within retinal pigment epithelial cells in patients with either Best or Stargardt dystrophy, functional findings pertaining to recovery of rod dark adaptation thresholds as well as electro-oculogram light peak to dark trough ratios are different in these two disorders.
引用
收藏
页码:430 / 432
页数:3
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