10 '-Chloro-3 ',4 '-dihydro-2 ' H-spiro[cyclopropane-1,7 '(6 ' H)-pyrimido[2,1-a]isoquinolin]-6 '-one

被引：0

作者：

Okuda, Kensuke ^{[1
]}

Hirota, Takashi ^{[2
]}

Nishina, Yuta ^{[3
]}

Ishida, Hiroyuki ^{[4
]}

机构：

[1] Gifu Pharmaceut Univ, Lab Med & Pharmaceut Chem, Gifu 5011196, Japan

[2] Okayama Univ, Fac Pharmaceut Sci, Lab Pharmaceut Chem, Okayama 7008530, Japan

[3] Okayama Univ, Res Core Interdisciplinary Sci, Okayama 7008530, Japan

[4] Okayama Univ, Fac Sci, Dept Chem, Okayama 7008530, Japan

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS | 2012年 / 68卷

关键词：

data-to-parameter ratio = 20.6; mean ̄(C-C) = 0.002 Å; R factor = 0.031; single-crystal X-ray study; T = 180 K; wR factor = 0.079;

D O I：

10.1107/S1600536812044261

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

In the title compound, C14H13ClN2O, the fused hydropyrimidine ring adopts an envelope conformation with one of the methylene C atoms at the flap. The three-membered ring is approximately perpendicular to the attached isoquinoline ring system, with a dihedral angle of 89.44 (11)degrees. In the crystal, molecules are linked by a weak C-H center dot center dot center dot pi interaction, forming a helical chain along the c axis.

引用

页码：O3252 / +

页数：8

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