BRAIN ATROPHY ON COMPUTERIZED AXIAL-TOMOGRAPHY SCANS - INTERACTION OF AGE, DIABETES AND GENERAL MORBIDITY

被引：22
作者：
PIRTTILA, T
JARVENPAA, R
LAIPPALA, P
FREY, H
机构：
[1] TAMPERE UNIV,CENT HOSP,DEPT RADIOL,TAMPERE,FINLAND
[2] UNIV TAMPERE,DEPT PUBL HLTH,TAMPERE,FINLAND
来源：
GERONTOLOGY | 1992年 / 38卷 / 05期
关键词：
AGE; BRAIN ATROPHY; COMPUTERIZED AXIAL TOMOGRAPHY; CEREBROVASCULAR DISEASES; DIABETES;
D O I：
10.1159/000213342
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
We evaluated, retrospectively, the occurrence of brain atrophy in all patients (n = 416) with a brain CT scan performed during a 3-month period in 1989 at the Tampere University Central Hospital. Age, diabetes, hypertension, chronic cerebrovascular disorders and an increasing number of medications were associated with brain atrophy in the log-linear models. We suggest that the effect of various systemic medical disorders on the brain requires consideration when evaluating and assessing physiological ageing of the brain.
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页码：285 / 291
页数：7
相关论文
共 31 条
[1]   HYPOTHALAMIC AND CORTICAL-NEURONS OF NORMOTENSIVE AND SPONTANEOUSLY HYPERTENSIVE RATS ARE DIFFERENTLY AFFECTED BY STREPTOZOTOCIN DIABETES [J].
AFFOLTER, V ;
BOUJON, P ;
BESTETTI, G ;
ROSSI, GL .
ACTA NEUROPATHOLOGICA, 1986, 70 (02) :135-141
[2]   COMPUTERIZED AXIAL-TOMOGRAPHY IN THE DETECTION OF BRAIN-DAMAGE .2. EPILEPSY, MIGRAINE, AND GENERAL MEDICAL DISORDERS [J].
CALA, LA ;
MASTAGLIA, FL .
MEDICAL JOURNAL OF AUSTRALIA, 1980, 2 (11) :616-620
[3]   EFFECT OF EXPERIMENTAL DIABETES ON THE LEVELS OF AROMATIC AND BRANCHED-CHAIN AMINO-ACIDS IN RAT-BLOOD AND BRAIN [J].
CRANDALL, EA ;
FERNSTROM, JD .
DIABETES, 1983, 32 (03) :222-230
[4]   VENTRICLE SIZE, CORTICAL ATROPHY AND THE RELATIONSHIP WITH NEUROPSYCHOLOGICAL STATUS IN CLOSED HEAD-INJURY - A QUANTITATIVE-ANALYSIS [J].
CULLUM, CM ;
BIGLER, ED .
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY, 1986, 8 (04) :437-452
[5]   CT IN THE DIFFERENTIAL-DIAGNOSIS BETWEEN ALZHEIMERS-DISEASE AND VASCULAR DEMENTIA [J].
ERKINJUNTTI, T ;
KETONEN, L ;
SULKAVA, R ;
VUORIALHO, M ;
PALO, J .
ACTA NEUROLOGICA SCANDINAVICA, 1987, 75 (04) :262-270
[6]   COMPUTERIZED AXIAL TOMOGRAMS AND DEMENTIA IN ELDERLY PATIENTS [J].
FORD, CV ;
WINTER, J .
JOURNALS OF GERONTOLOGY, 1981, 36 (02) :164-169
[7]  
FREEMAN DH, 1987, APPLIED CATEGORIAL D
[8]  
GREVE E, 1989, SCAND J SOC MED, V17, P147
[9]   ASSOCIATION OF HYPERTENSION WITH INCREASED ATROPHY OF BRAIN MATTER IN THE ELDERLY [J].
HATAZAWA, J ;
YAMAGUCHI, T ;
ITO, M ;
YAMAURA, H ;
MATSUZAWA, T .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 1984, 32 (05) :370-374
[10]   COMPUTED-TOMOGRAPHY BRAIN CHANGES IN PARKINSONIAN DEMENTIA [J].
INZELBERG, R ;
TREVES, T ;
REIDER, I ;
GERLENTER, I ;
KORCZYN, AD .
NEURORADIOLOGY, 1987, 29 (06) :535-539
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