INTESTINAL GOBLET CELL-DIFFERENTIATION IN NIPPOSTRONGYLUS-INFECTED RATS AFTER TRANSFER OF FRACTIONATED THORACIC-DUCT LYMPHOCYTES

被引:54
作者
MILLER, HRP
NAWA, Y
PARISH, CR
机构
[1] AUSTRALIAN NATL UNIV, JOHN CURTIN SCH MED RES, DEPT MICROBIOL, CANBERRA 2601, ACT, AUSTRALIA
[2] AUSTRALIAN NATL UNIV, JOHN CURTIN SCH MED RES, DEPT IMMUNOL, CANBERRA 2601, ACT, AUSTRALIA
来源
INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY | 1979年 / 59卷 / 03期
关键词
D O I
10.1159/000232271
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Adoptive immunization of Nippostrongylus-infected rats augmented goblet cell differentiation in the intestinal epithelium. After fractionation of immune thoracic duct lymphocytes (TDL), cells lacking surface immunoglobulin (sIg-) were the most potent stimulators of goblet cell differentiation. TDL drained from rats harboring a primary infection were more effective than TDL from hyperimmune rats.
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收藏
页码:281 / 285
页数:5
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