Ranibizumab treatment of retinal vein occlusion

被引：0

作者：

Johnson, Robert N. ^{[1
]}

机构：

[1] Calif Pacific Med Ctr, Dept Ophthalmol, San Francisco, CA 94114 USA

来源：

EXPERT REVIEW OF OPHTHALMOLOGY | 2012年 / 7卷 / 06期

关键词：

branch retinal vein occlusion; central retinal vein occlusion; Lucentis (R); ranibizumab; retinal vein occlusion; VEGF;

D O I：

10.1586/EOP.12.59

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

The development and approval of anti-VEGF drugs for intravitreal injection has transformed the treatment and prognosis of several ocular conditions, including age-related macular degeneration and retinal vascular occlusion (the subject of this article). Their role in the treatment of ocular conditions is likely to continue to expand owing to the common pathway that VEGF plays in multiple retinal disorders. While important strides have been made, an important treatment challenge is the dosing frequency and the burden that this places on the patient and healthcare providers.

引用

页码：509 / 515

页数：7

共 30 条

[1] INCREASED VASCULAR ENDOTHELIAL GROWTH-FACTOR LEVELS IN THE VITREOUS OF EYES WITH PROLIFERATIVE DIABETIC-RETINOPATHY [J].

ADAMIS, AP ;

MILLER, JW ;

BERNAL, MT ;

DAMICO, DJ ;

FOLKMAN, J ;

YEO, TK ;

YEO, KT .

AMERICAN JOURNAL OF OPHTHALMOLOGY, 1994, 118 (04) :445-450

[2] VASCULAR ENDOTHELIAL GROWTH-FACTOR IN OCULAR FLUID OF PATIENTS WITH DIABETIC-RETINOPATHY AND OTHER RETINAL DISORDERS [J].

AIELLO, LP ;

AVERY, RL ;

ARRIGG, PG ;

KEYT, BA ;

JAMPEL, HD ;

SHAH, ST ;

PASQUALE, LR ;

THIEME, H ;

IWAMOTO, MA ;

PARK, JE ;

NGUYEN, HV ;

AIELLO, LM ;

FERRARA, N ;

KING, GL .

NEW ENGLAND JOURNAL OF MEDICINE, 1994, 331 (22) :1480-1487

[3]

[Anonymous], 1984, AM J OPHTHALMOL, V98, P271

[4] Pharmacokinetics of intravitreal ranibizumab (Lucentis) [J].

Bakri, Sophie J. ;

Snyder, Melissa R. ;

Reid, Joel M. ;

Pulido, Jose S. ;

Ezzat, Mohamed K. ;

Singh, Ravinder J. .

OPHTHALMOLOGY, 2007, 114 (12) :2179-2182

[5] Vascular Endothelial Growth Factor Trap-Eye for Macular Edema Secondary to Central Retinal Vein Occlusion Six-Month Results of the Phase 3 COPERNICUS Study [J].

Boyer, David ;

Heier, Jeffrey ;

Brown, David M. ;

Clark, W. Lloyd ;

Vitti, Robert ;

Berliner, Alyson J. ;

Groetzbach, Georg ;

Zeitz, Oliver ;

Sandbrink, Rupert ;

Zhu, Xiaoping ;

Beckmann, Karola ;

Haller, Julia A. .

OPHTHALMOLOGY, 2012, 119 (05) :1024-1032

[6]

Boyer D, 2010, OPHTHALMOLOGY, V117, P1860, DOI 10.1016/j.ophtha.2010.02.022

[7] A Phase IIIb Study to Evaluate the Safety of Ranibizumab in Subjects with Neovascular Age-related Macular Degeneration [J].

Boyer, David S. ;

Heier, Jeffrey S. ;

Brown, David M. ;

Francom, Steven F. ;

Ianchulev, Tsontcho ;

Rubio, Roman G. .

OPHTHALMOLOGY, 2009, 116 (09) :1731-1739

[8] Sustained Benefits from Ranibizumab for Macular Edema Following Branch Retinal Vein Occlusion: 12-Month Outcomes of a Phase III Study [J].

Brown, David M. ;

Campochiaro, Peter A. ;

Bhisitkul, Robert B. ;

Ho, Allen C. ;

Gray, Sarah ;

Saroj, Namrata ;

Adamis, Anthony P. ;

Rubio, Roman G. ;

Murahashi, Wendy Yee .

OPHTHALMOLOGY, 2011, 118 (08) :1594-1602

[9] Sustained Benefits from Ranibizumab for Macular Edema following Central Retinal Vein Occlusion: Twelve-Month Outcomes of a Phase III Study [J].

Campochiaro, Peter A. ;

Brown, David M. ;

Awh, Carl C. ;

Lee, S. Young ;

Gray, Sarah ;

Saroj, Namrata ;

Murahashi, Wendy Yee ;

Rubio, Roman G. .

OPHTHALMOLOGY, 2011, 118 (10) :2041-2049

[10] Ranibizumab for Macular Edema following Branch Retinal Vein Occlusion Six-Month Primary End Point Results of a Phase III Study [J].

Campochiaro, Peter A. ;

Heier, Jeffrey S. ;

Feiner, Leonard ;

Gray, Sarah ;

Saroj, Namrata ;

Rundle, Amy Chen ;

Murahashi, Wendy Yee ;

Rubio, Roman G. .

OPHTHALMOLOGY, 2010, 117 (06) :1102-U111

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