EFFECTS OF ADENOSINE ON CHRONOTROPIC RESPONSES OF RAT ATRIA TO ALPHA-ADRENERGIC AND BETA-ADRENERGIC STIMULATION

被引:0
|
作者
GENDE, OA
机构
[1] Centro de Investigaliones Cardiovasculares, Facultad de Ciencias Medicas, Universidad Nacional de La Plata, La Plata
来源
ARCHIVES INTERNATIONALES DE PHYSIOLOGIE DE BIOCHIMIE ET DE BIOPHYSIQUE | 1993年 / 101卷 / 06期
关键词
ADENOSINE; ADRENERGIC STIMULATION; RAT ATRIA;
D O I
10.3109/13813459309046987
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The chronotropic response of rat atria to beta adrenergic stimulation required higher concentrations of agonist in the presence of adenosine. This anti beta-adrenergic effect could attenuate the tachycardia induced by the increased sympathetic tone during cardiac ischemia. The sensitivity to alpha adrenergic stimulation did not change in the presence of adenosine.
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页码:329 / 331
页数:3
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