EFFECTS OF ADENOSINE ON CHRONOTROPIC RESPONSES OF RAT ATRIA TO ALPHA-ADRENERGIC AND BETA-ADRENERGIC STIMULATION

被引:0
作者
GENDE, OA
机构
[1] Centro de Investigaliones Cardiovasculares, Facultad de Ciencias Medicas, Universidad Nacional de La Plata, La Plata
来源
ARCHIVES INTERNATIONALES DE PHYSIOLOGIE DE BIOCHIMIE ET DE BIOPHYSIQUE | 1993年 / 101卷 / 06期
关键词
ADENOSINE; ADRENERGIC STIMULATION; RAT ATRIA;
D O I
10.3109/13813459309046987
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The chronotropic response of rat atria to beta adrenergic stimulation required higher concentrations of agonist in the presence of adenosine. This anti beta-adrenergic effect could attenuate the tachycardia induced by the increased sympathetic tone during cardiac ischemia. The sensitivity to alpha adrenergic stimulation did not change in the presence of adenosine.
引用
收藏
页码:329 / 331
页数:3
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