PARATHYROID-HORMONE RELATED PROTEIN (PTHRP) AND BREAST-CANCER

被引：0
|
作者：
DEVERNEJOUL, MC
BOUIZAR, Z
LASMOLES, F
TUBIANAHULIN, M
SPYRATOS, F
GUERIS, J
JULLIENNE, A
机构：
来源：
NOUVELLE REVUE FRANCAISE D HEMATOLOGIE | 1991年 / 33卷 / 06期
关键词：
PTHRP; BREAST CANCER; HYPERCALCEMIA; WALKER CARCINOMA;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
PTHrP, a newly caracterized peptide is responsible for humoral hyperclcemia of malignancy in squamous cancers. It is also expressed by a variety of normal tissue and might have growth factor propriety. It is expressed by lactating breast and is frequently present in breast cancer. Although it is responsible for humoral hypercalcemia in an animal model of breast cancer its role in breast cancer hypercalcemia is still putative. The possibility that it might be one of the autocrine growth factors implicated in breast cancer cell proliferation has been suggested.
引用
收藏
页码：485 / 487
页数：3
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