COMPARISON OF PIVMECILLINAM AND CEPHRADINE IN BACTERIURIA IN PREGNANCY AND IN ACUTE URINARY-TRACT INFECTION

被引：20

作者：

BRUMFITT, W ^{[1
]}

FRANKLIN, I ^{[1
]}

HAMILTONMILLER, J ^{[1
]}

ANDERSON, F ^{[1
]}

机构：

[1] EDGWARE GEN HOSP,LONDON,ENGLAND

来源：

SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES | 1979年 / 11卷 / 04期

关键词：

D O I：

10.3109/inf.1979.11.issue-4.04

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

48 non-pregnant domiciliary patients referred by general practitioners and 50 pregnant women were treated for bacteriuria with either 500 mg cephradine or 400 mg pivmecillinam every 6 h for 7 days. In the pregnant women, cure rates were over 90% after 2 weeks for both compounds, and after 6 weeks were 86 % for cephradine and 78 % for pivmecillinam. Cure rates in the non-pregnant patients were 83% for cephradine and 95 % for pivmecillinam at 6 weeks. Seven patients (3 given cephradine, 4 given pivmecillinam) stopped treatment due to side-effects. Overall, side-effects (many of which were trivial) were more common in patients treated with cephradine (51 %) than in those receiving pivmecillinam (33 %). It is concluded that both drugs are highly effective in these two common types of urinary infection. © 1979, Informa UK Ltd. All rights reserved.

引用

页码：275 / 279

页数：5

共 18 条

[1] CONTROLLED RANDOMIZED STUDY COMPARING AMOXYCILLIN AND PIVMECILLINAM IN ADULT OUT-PATIENTS PRESENTING WITH SYMPTOMS OF ACUTE URINARY-TRACT INFECTION [J].