STUDIES ON FUNGAL PRODUCTS .33. STRUCTURES OF NEW INDOLODITERPENES, POSSIBLE BIOSYNTHETIC PRECURSORS OF THE TREMORGENIC MYCOTOXINS, PENITREMS, FROM PENICILLIUM-CRUSTOSUM

被引：26
作者：
HOSOE, T
NOZAWA, K
UDAGAWA, S
NAKAJIMA, S
KAWAI, K
机构：
[1] HOSHI UNIV, FAC PHARMACEUT SCI, EBARA 2-4-41, SHINAGAWA KU, TOKYO 142, JAPAN
[2] NATL INST HYG SCI, SETAGAYA KU, TOKYO 158, JAPAN
来源：
CHEMICAL & PHARMACEUTICAL BULLETIN | 1990年 / 38卷 / 12期
关键词：
PENICILLIUM-CRUSTOSUM; MYCOTOXIN; INDOLODITERPENE; PENITREM-A; PENITREM-B; PENITREM-C; PENITREM-D; PENITREM-E; PENITREM-F; PC-M5'; PC-M6; BIOSYNTHETIC PRECURSOR;
D O I：
10.1248/cpb.38.3473
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Along with the tremorgenic mycotoxins, penitrems A (3), B (4), D (6), E (7), and F (8), the minor metabolites 1 and 2 were isolated from the mycelia of Penicillium crustosum THOM, which was found contaminating bread intended for school lunches in Tokyo city. The structures of 1 and 2 were determined on the basis of spectroscopic and chemical investigations. These compounds (1 and 2) might be biosynthetic precursors of penitrems.
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页码：3473 / 3475
页数：3
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