GAS-LIQUID-CHROMATOGRAPHIC SEPARATION OF SOME OPTICALLY-ACTIVE AMINES BY DIASTEREOMER FORMATION

被引：16
作者：
MANIUS, G
TSCHERNE, R
机构：
[1] Analytical Research Laboratory, Quality Control Department, Hoffmann La Roche Inc., Nutley, NJ
来源：
JOURNAL OF CHROMATOGRAPHIC SCIENCE | 1979年 / 17卷 / 06期
关键词：
D O I：
10.1093/chromsci/17.6.322
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Methods for the separation of the enantiomers of some important, optically active amines have been developed. Gas-liquid chromatography is used to separate the diastereomers formed by the coupling of the amines to an optically active compound. All separations are achieved on a conventional, optically inactive column. A discussion of reasons for the successes and failures with certain compounds is presented. © 1979, Oxford University Press. All rights reserved.
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页码：322 / 326
页数：5
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