ASYMMETRIC SYNTHESIS OF 2-ALKYLCYCLOHEXANONES ON SOLID-PHASES

被引：58

作者：

WORSTER, PM

MCARTHUR, CR

LEZNOFF, CC

机构：

[1] York University, Department of Chemistry, Toronoto, Ontario, M3J 1P3, Downsview

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1979年 / 18卷 / 03期

关键词：

D O I：

10.1002/anie.197902211

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Asymmetric syntheses on a kind of “Synthetic enzyme” appear highly promising, as shown by the reaction sequence illustrated below: S‐2‐methyl‐and S‐2‐propycyclohexanone have each been obtained in 80% chemical yield and 95 and 60% optical yield, respectively. The chiral reagent 1 can be re‐used. (Figure Presented.) Copyright © 1979 by Verlag Chemie, GmbH, Germany

引用

页码：221 / 222

页数：2

共 14 条

[1] ASYMMETRIC CATALYTIC REDUCTION WITH TRANSITION-METAL COMPLEXES .2. ASYMMETRIC CATALYSIS BY A SUPPORTED CHIRAL RHODIUM COMPLEX
DUMONT, W
POULIN, J
DANG, T
KAGAN, HB
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1973, 95 (25) : 8295 - 8299
[2] ASYMMETRIC SYNTHESIS OF ALPHA-SUBSTITUTED KETONES BY METALATION AND ALKYLATION OF CHIRAL HYDRAZONES
ENDERS, D
EICHENAUER, H
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1976, 15 (09): : 549 - 551
[3] Enders D., 1976, ANGEW CHEM-GER EDIT, V88, P579
[4] KAWANA M, 1972, TETRAHEDRON LETT, P4855
[5] KIECZYKOWSKI GR, 1976, TETRAHEDRON LETT, P597
[6] KITAMOTO M, 1974, CHEM PHARM BULL, V22, P459
[7] ORGANOTIN HYDRIDES AND ORGANIC FREE RADICALS
KUIVILA, HG
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1968, 1 (10) : 299 - &
[8] USE OF INSOLUBLE POLYMER SUPPORTS IN GENERAL ORGANIC-SYNTHESIS
LEZNOFF, CC
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1978, 11 (09) : 327 - 333
[9] ENANTIOSELECTIVE ALKYLATION OF CYCLOHEXANONE VIA CHIRAL LITHIO-CHELATED ENAMINES
MEYERS, AI
WILLIAMS, DR
DRUELINGER, M
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (10) : 3032 - 3033
[10] TAKAISKI N, 1978, J AM CHEMICAL SOC, V100, P268

← 1 2 →