SYNTHESIS ON SOLID PEPTIDE SUPPORTS WITH A C-TERMINAL AMINO ALCOHOL RESIDUE

被引：8

作者：

MOLLE, G

DUGAST, JY

机构：

[1] Laboratoire de Chimie Macromoléculaire, associé au CNRS, Faculté des Sciences de Rouen

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 44期

关键词：

D O I：

10.1016/S0040-4039(00)97062-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The solid-phase synthesis of alamethicin analogues with a γ-carboxylic group or glutamic acid was achieved by anchoring an aminoalcohol via succinic anhydride on benzhydrilamine resin. By controlling the ester interchange, an alkaline hydrolysis allowed to obtain either the Free Glu8 peptide-ol or its Glu8 methylester. © 1990.

引用

页码：6355 / 6356

页数：2

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