A MILK PROTEIN GENE PROMOTER DIRECTS THE EXPRESSION OF HUMAN-TISSUE PLASMINOGEN-ACTIVATOR CDNA TO THE MAMMARY-GLAND IN TRANSGENIC MICE

被引：162
作者：
PITTIUS, CW
HENNIGHAUSEN, L
LEE, E
WESTPHAL, H
NICOLS, E
VITALE, J
GORDON, K
机构：
[1] NIDDKD,BLDG 10,ROOM 9N-113,BETHESDA,MD 20892
[2] NICHHD,BETHESDA,MD 20892
[3] INTEGRATED GENET,FRAMINGHAM,MA 01701
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1988年 / 85卷 / 16期
关键词：
D O I：
10.1073/pnas.85.16.5874
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：5874 / 5878
页数：5
相关论文
共 26 条
[1]   HA-RAS ONCOGENE EXPRESSION DIRECTED BY A MILK PROTEIN GENE PROMOTER - TISSUE-SPECIFICITY, HORMONAL-REGULATION, AND TUMOR-INDUCTION IN TRANSGENIC MICE [J].
ANDRES, AC ;
SCHONENBERGER, CA ;
GRONER, B ;
HENNIGHAUSEN, L ;
LEMEUR, M ;
GERLINGER, P .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (05) :1299-1303
[2]  
[Anonymous], 1986, MANIPULATING MOUSE E
[3]   PURIFICATION OF BIOLOGICALLY-ACTIVE GLOBIN MESSENGER-RNA BY CHROMATOGRAPHY ON OLIGOTHYMIDYLIC-ACID-CELLULOSE [J].
AVIV, H ;
LEDER, P .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1972, 69 (06) :1408-&
[4]   COMPARISON OF THE WHEY ACIDIC PROTEIN GENES OF THE RAT AND MOUSE [J].
CAMPBELL, SM ;
ROSEN, JM ;
HENNIGHAUSEN, LG ;
STRECHJURK, U ;
SIPPEL, AE .
NUCLEIC ACIDS RESEARCH, 1984, 12 (22) :8685-8697
[5]   THE MOUSE MAMMARY-TUMOR VIRUS LONG TERMINAL REPEAT DIRECTS EXPRESSION IN EPITHELIAL AND LYMPHOID-CELLS OF DIFFERENT TISSUES IN TRANSGENIC MICE [J].
CHOI, YW ;
HENRARD, D ;
LEE, IC ;
ROSS, SR .
JOURNAL OF VIROLOGY, 1987, 61 (10) :3013-3019
[6]   SINGLE-STEP METHOD OF RNA ISOLATION BY ACID GUANIDINIUM THIOCYANATE PHENOL CHLOROFORM EXTRACTION [J].
CHOMCZYNSKI, P ;
SACCHI, N .
ANALYTICAL BIOCHEMISTRY, 1987, 162 (01) :156-159
[7]   PHARMACEUTICALS FROM TRANSGENIC LIVESTOCK [J].
CLARK, AJ ;
SIMONS, P ;
WILMUT, I ;
LATHE, R .
TRENDS IN BIOTECHNOLOGY, 1987, 5 (01) :20-24
[8]   A TECHNIQUE FOR RADIOLABELING DNA RESTRICTION ENDONUCLEASE FRAGMENTS TO HIGH SPECIFIC ACTIVITY [J].
FEINBERG, AP ;
VOGELSTEIN, B .
ANALYTICAL BIOCHEMISTRY, 1983, 132 (01) :6-13
[9]   PRODUCTION OF HUMAN-TISSUE PLASMINOGEN-ACTIVATOR IN TRANSGENIC MOUSE MILK [J].
GORDON, K ;
LEE, E ;
VITALE, JA ;
SMITH, AE ;
WESTPHAL, H ;
HENNIGHAUSEN, L .
BIO-TECHNOLOGY, 1987, 5 (11) :1183-&
[10]   STUDY OF PROTEASES AND PROTEASE-INHIBITOR COMPLEXES IN BIOLOGICAL-FLUIDS [J].
GRANELLIPIPERNO, A ;
REICH, E .
JOURNAL OF EXPERIMENTAL MEDICINE, 1978, 148 (01) :223-234
123