RAPID, COMPREHENSIVE SCREENING-PROCEDURE FOR BASIC DRUGS IN BLOOD OR TISSUES BY GAS-CHROMATOGRAPHY

被引:129
作者
FOERSTER, EH [1 ]
HATCHETT, D [1 ]
GARRIOTT, JC [1 ]
机构
[1] SW INST FORENS SCI,TOXICOL LAB,POB 35728,DALLAS,TX 75235
关键词
D O I
10.1093/jat/2.2.50
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A method is described for the comprehensive screening and analysis of more than 80 basic compounds and metabolites in blood and other biological specimens. The method of Foerster and Mason using 1-chlorobutane as the extracting solvent with gas chromatographic analysis has been further developed and modified so that identification and quantitation of as little as 0.1 μg/ml of virtually all basic drugs in blood can be accomplished in approximately one and one-half hours.
引用
收藏
页码:50 / 55
页数:6
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