Specification of Primary Nucleotide Sequence and Exon-Intron Structure of Rattus norvegicus Acetylcholinesterase Gene

被引：0

作者：

Lannik, N. I. ^{[1
]}

Tarasov, D. S. ^{[2
,3
]}

Petrov, K. A. ^{[4
,5
]}

Bukharaeva, E. A. ^{[4
,5
]}

Nikolskii, E. E. ^{[5
,6
]}

Rizvanov, A. A. ^{[1
,7
]}

机构：

[1] Kazan Privolzhsky Fed Univ, Dept Genet, Kazan, Russia

[2] Kazan Privolzhsky Fed Univ, Biol Sci, Kazan, Russia

[3] Kazan Privolzhsky Fed Univ, Dept Biochem, Kazan, Russia

[4] RAS, Kazan Inst Biochem & Biophys, Biol Sci, Moscow, Russia

[5] RAS, Kazan Inst Biochem & Biophys, Moscow, Russia

[6] Russian Acad Sci, Med Sci, Moscow 117901, Russia

[7] Kazan Privolzhsky Fed Univ, Biol, Kazan, Russia

来源：

UCHENYE ZAPISKI KAZANSKOGO UNIVERSITETA-SERIYA ESTESTVENNYE NAUKI | 2011年 / 153卷 / 01期

关键词：

acetylcholinesterase; alternative splicing; PCR; sequencing;

D O I：

暂无

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The purpose of this study was to specify the nucleotide sequence and structure of the acetylcholinesterase (AChE) gene of Rattus norvegicus. During an analysis of rat genomic DNA sequence data obtained in the course of the project Rat Genome Sequencing Consortium (RGSC) (NW_001084677,1), the authors found gaps of 229 nucleotides at the 5'-end and 391 nucleotides at the 3'-end of AChE gene. These gaps were sequenced and analysed. A computer model of R. norvegicus AChE gene structure was developed based on multiple alignment, analysis of EST-sequences database, and using methods of bioinformatics.

引用

页码：103 / 105

页数：3

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