Panuveitis as syphilis manifestation in HIV-1 infected patients

Syphilis prevalence has been on the rise worldwide, including Poland, for the last 5 years, most often affecting young individuals who have unprotected intercourse. Currently most syphilitic patients, if diagnosed, are treated early and more advanced disease is rarely seen. We present a case of two individuals with AIDS and advanced syphilis with ocular in-volvement which was the reason to test for syphilis. It is worth reminding that syphilis and HIV share the same route of infection and in the light of recent epidemiological data it is wor-th considering if universal screening for syphilis is needed once again just like universal scre-ening for HIV has become the standard of care in many countries.