HYDROLASES IN ORGANIC-SYNTHESIS - PREPARATION OF ENANTIOMERICALLY PURE COMPOUNDS

被引：25

作者：

ADER, U

ANDERSCH, P

BERGER, M

GOERGENS, U

SEEMAYER, R

SCHNEIDER, M

机构：

[1] FB 9 - Bergische Universitat-GH-Wuppertal, D-5600

来源：

PURE AND APPLIED CHEMISTRY | 1992年 / 64卷 / 08期

关键词：

D O I：

10.1351/pac199264081165

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Esterhydrolases ( Esterases , Lipases ) are highly ( chemo-, regio- and enantio- ) selective biocatalysts for the transformation of racemic and achiral substrates into enantiomerically pure compounds. Numerous examples for their application in the preparation of synthetically useful chiral auxiliaries and building blocks for flavour compounds, pheromones and several pharmaceuticals including beta-adrenergic blockers, antidepressants and ACE inhibitors are presented.

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页码：1165 / 1170

页数：6

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