DISTRIBUTION OF THE RESIDENT ORAL BACTERIAL-POPULATIONS IN DIFFERENT STRAINS OF MICE

被引:13
作者
GADBOIS, T [1 ]
MARCOTTE, H [1 ]
RODRIGUE, L [1 ]
COULOMBE, C [1 ]
GOYETTE, N [1 ]
LAVOIE, MC [1 ]
机构
[1] UNIV LAVAL, FAC MED DENT, RECH ECOL BUCCALE GRP, QUEBEC CITY G1K 7P4, QUEBEC, CANADA
关键词
ENVIRONMENT; BACTERIAL ECOLOGY; RESIDENT ORAL MICROBIOTA; MICE; BACTERIAL BIOTA; GENETIC BACKGROUND;
D O I
10.3109/08910609309141333
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The distribution of the resident oral bacterial species was evaluated in six genetically different mouse strains (BALB/c, C3H/He, C57BL/6, C57BL/10, DBA/2 and CD-1). The results indicate that these mouse strains harbour different oral microbiota upon arrival at our animal facilities. However, this difference persists only in strains C57BL/10 and DBA/2 1 wk after arrival. Except for strains CD-1 and C57BL/10, the oral biota is different upon arrival compared to that observed after 1 wk at our animal facilities. For the same mouse strain, the oral biota can differ significantly from one shipment to another upon arrival but tends to stabilise after 1 wk. This stabilising effect can be related to the increase in the proportion of Lactobacillus murinus among the total cultivable oral microbiota. These results indicate that if the host genetic background influences the distribution of the oral bacterial populations, its effect is masked by environmental factors.
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页码:245 / 251
页数:7
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