APAMIN INCREASES NMDA-INDUCED BURST-FIRING OF RAT MESENCEPHALIC DOPAMINE NEURONS

被引：93

作者：

SEUTIN, V ^{[1
]}

JOHNSON, SW ^{[1
]}

NORTH, RA ^{[1
]}

机构：

[1] OREGON HLTH SCI UNIV, VOLLUM INST, PORTLAND, OR 97201 USA

来源：

BRAIN RESEARCH | 1993年 / 630卷 / 1-2期

关键词：

APAMIN; VENTRAL TEGMENTAL AREA; BURST-FIRING;

D O I：

10.1016/0006-8993(93)90675-D

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Intracellular recordings made in vitro from rat midbrain dopamine neurons showed that apamin (100 nM) did not alter the regular spontaneous firing of the neurons, but it increased the occurrence of bursts of action potentials in N-methyl-D-aspartate. Apamin appeared to facilitate burst-firing induced by NMDA because, by blocking an outward calcium-activated potassium current, it increased the depolarizing action of NMDA.

引用

页码：341 / 344

页数：4

共 50 条

[11] ELECTROPHYSIOLOGY AND BURST-FIRING OF RAT SUBICULAR PYRAMIDAL NEURONS INVITRO - A COMPARISON WITH AREA CA1
MASON, A
BRAIN RESEARCH, 1993, 600 (01) : 174 - 178
[12] REPETITIVE BURST-FIRING NEURONS IN THE DEEP LAYERS OF MOUSE SOMATOSENSORY CORTEX
AGMON, A
CONNORS, BW
NEUROSCIENCE LETTERS, 1989, 99 (1-2) : 137 - 141
[13] Nitric oxide regulates NMDA-induced dopamine release in rat striatum
Shibata, M
Araki, N
Ohta, K
Hamada, J
Shimazu, K
Fukuuchi, Y
NEUROREPORT, 1996, 7 (02) : 605 - 608
[14] THE CONTROL OF FIRING PATTERN IN NIGRAL DOPAMINE NEURONS - BURST FIRING
GRACE, AA
BUNNEY, BS
JOURNAL OF NEUROSCIENCE, 1984, 4 (11): : 2877 - 2890
[15] EFFECT OF 7-CHLOROKYNURENIC ACID AND GLYCINE ON NMDA-INDUCED EXCITATION OF RAT DOPAMINE AND HIPPOCAMPAL-NEURONS
GOBELS, T
SEUTIN, V
MASSOTTE, L
DRESSE, A
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1995, 430 (05): : 30 - 30
[16] Food Restriction Increases Glutamate Receptor-Mediated Burst Firing of Dopamine Neurons
Branch, Sarah Y.
Goertz, R. Brandon
Sharpe, Amanda L.
Pierce, Janie
Roy, Sudip
Ko, Daijin
Paladini, Carlos A.
Beckstead, Michael J.
JOURNAL OF NEUROSCIENCE, 2013, 33 (34): : 13861 - 13872
[17] Neurochemical identification of stereotypic burst-firing neurons in the rat dorsal raphe nucleus using juxtacellular labelling methods
Hajos, Mihaly
Allers, Kelly A.
Jennings, Katie
Sharp, Trevor
Charette, Guy
Sik, Attila
Kocsis, Bernat
EUROPEAN JOURNAL OF NEUROSCIENCE, 2007, 25 (01) : 119 - 126
[18] Chronic social defeat stress-induced enhancement of T-type calcium channels increases burst-firing neurons in the ventral subiculum
Lee, Soonje
Lee, Changwoo
Woo, Changsu
Kang, Shin Jung
Shin, Ki Soon
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 508 (04) : 1182 - 1187
[19] Humanin Rescues Cultured Rat Cortical Neurons from NMDA-Induced Toxicity Not by NMDA Receptor
Cui, Ai-Ling
Li, Jian-Zhong
Feng, Zhi-Bo
Ma, Guo-Lin
Gong, Liang
Li, Chun-Ling
Zhang, Ce
Li, Kefeng
SCIENTIFIC WORLD JOURNAL, 2014,
[20] PHENOBARBITAL - CONCENTRATION-DEPENDENT BIPHASIC EFFECT ON APLYSIA BURST-FIRING NEURONS
JOHNSTON, D
NEUROSCIENCE LETTERS, 1978, 10 (1-2) : 175 - 180

← 1 2 3 4 5 →