SYNTHESIS OF 5-THIO-L-FUCOSE AND ITS INHIBITORY EFFECT ON FUCOSIDASE

被引：63

作者：

HASHIMOTO, H

FUJIMORI, T

YUASA, H

机构：

[1] Department of Life Science, Faculty of Science, Tokyo Institute of Technology, Nagatsuta, Midoriku

来源：

JOURNAL OF CARBOHYDRATE CHEMISTRY | 1990年 / 9卷 / 05期

关键词：

D O I：

10.1080/07328309008543863

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

5-Thio-L-fucose was synthesized for the first time from D-glucose in 16 steps and-foundto have a remarkable inhibitory effect on fucosidases from bovine epididymis (Ki 4.2 x 10-5 M) and kidney (Ki 8.4xl0-5 M). © 1990, Taylor & Francis Group, LLC. All rights reserved.

引用

页码：683 / 694

页数：12

共 10 条

[1]

ANISUZZAMAN AKM, 1977, CARBOHYD RES, V55, P205

[2]

CHEN M, 1976, Miscellaneous Papers Landbouwhogeschool Wageningen, V12, P17

[3] 5-THIO-D-FRUCTOFURANOSE [J].