POLYCONDENSED HETEROCYCLES .7. A CONVENIENT SYNTHESIS OF PYRROLO[1,2-A]QUINOXALINE DERIVATIVES BY INTRAMOLECULAR AROMATIC NUCLEOPHILIC DISPLACEMENT

被引：26

作者：

CAMPIANI, G ^{[1
]}

NACCI, V ^{[1
]}

CORELLI, F ^{[1
]}

ANZINI, M ^{[1
]}

机构：

[1] UNIV SIENA,DIPARTIMENTO FARMACO CHIM TECNOL,BANCHI SOTTO 55,I-53100 SIENA,ITALY

来源：

SYNTHETIC COMMUNICATIONS | 1991年 / 21卷 / 15-16期

关键词：

D O I：

10.1080/00397919108021054

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

4-(4-Methyl-1-piperazinyl)-7-trifluoromethylpyrrolo[1,2-a]quinoxaline 1a (CGS 12066B) was described in 1987 as a highly selective agonist for the serotonin sensitive receptor subtype 5-HT1B1. Although the real selectivity of 1a for 5-HT1B versus 5-HT1A binding sites has been questioned2 more recently, yet compound 1a may prove a useful tool for the identification and the characterization of the putative receptor subtypes.

引用

页码：1567 / 1576

页数：10

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