MATERNAL TRANSMISSION OF SIVSMM IN RHESUS MACAQUES

被引:0
|
作者
MCCLURE, HM
ANDERSON, DC
FULTZ, PN
ANSARI, AA
JEHUDACOHEN, T
VILLINGER, F
KLUMPP, SA
SWITZER, W
LOCKWOOD, E
BRODIE, A
KEYSERLING, H
机构
[1] UNIV ALABAMA,DEPT MICROBIOL,BIRMINGHAM,AL 35294
[2] EMORY UNIV,SCH MED,DEPT PATHOL,ATLANTA,GA 30322
[3] EMORY UNIV,SCH MED,DEPT PEDIAT,ATLANTA,GA 30322
关键词
AIDS; ANIMAL MODELS; LENTIVIRUS; PERINATAL INFECTION;
D O I
暂无
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Fifteen SIV-infected rhesus monkeys delivered 13 livebirths and two stillbirths; one livebirth died at three days of age. While all infants were culture-negative for SIV at birth, nine had maternal antibodies that disappeared by six months of age. Three infants subsequently seroconverted and became virus positive at 9-15 months. Milk samples from all mothers were virus-negative at parturition but samples from four animals were virus-positive at nine and 12 months. This study documents maternal transmission of SIV and suggests transmission by breast-feeding.
引用
收藏
页码:182 / 187
页数:6
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