MORPHOLOGICAL AND ENDOCRINOLOGICAL DIFFERENCES BETWEEN THE ABDOMINAL TESTES IN BILATERAL AND UNILATERAL CRYPTORCHID RATS

被引：10

作者：

BERGH, A ^{[1
]}

DAMBER, JE ^{[1
]}

机构：

[1] UNIV UMEA,DEPT PHYSIOL,S-90187 UMEA,SWEDEN

来源：

INTERNATIONAL JOURNAL OF ANDROLOGY | 1979年 / 2卷 / 04期

关键词：

Cryptorchism; rat; stereology; testis; testosterone;

D O I：

10.1111/j.1365-2605.1979.tb00066.x

中图分类号：

R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

摘要：

Using a new experimental model of cryptorchism in rats, where testicular descent was prevented, testicular development and function were studied in bilateral and unilateral cryptorchid animals Morphometric and radioimmunological techniques were used. Up to 30 days after birth testicular development was identical in the two types of abdominal testes but in adult rats differences were observed. In these rats spermatogenesis was damaged to a similar extent, but total tubular length and testicular weight were increased in the bilateral abdominal testes. Moreover, in these testes, the volume density of Leydig cells, the total Leydig cell mass, the average Leydig cell size and the testis testosterone concentration were larger than in unilateral abdominal testes. It is suggested that the impaired spermatogenesis seen in both kinds of abdominal testes may be unrelated to Leydig cell function. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：319 / 329

页数：11