EFFECTS OF LEVAMISOLE AND D-PENICILLAMINE IN RAT PAW EDEMA INDUCED BY CARRAGEENAN AND BY KAOLIN

被引：5

作者：

TRANTER, BC ^{[1
]}

WEST, GB ^{[1
]}

机构：

[1] NE LONDON POLYTECH,DEPT PARAMED SCI,ROMFORD RD,LONDON E15 4LZ,ENGLAND

来源：

INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY | 1979年 / 59卷 / 03期

关键词：

D O I：

10.1159/000232281

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Levamisole potentiated paw oedema induced by carrageenan in the rat whereas penicillamine was without effect. On the other hand, levamisole inhibited paw oedema induced by kaolin, penicillamine again having no effect. The copper complex of penicillamine was inhibitory in the carrageenan test but failed to show inhibition in the kaolin model of inflammation. These results show that levamisole and penicillamine are capable of exerting anti-inflammatory activity in the rat but only under certain conditions. © 1979 S. Karger AG, Basel.

引用

页码：357 / 360

页数：4

共 6 条

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