PROPOSED REACTION-MECHANISM FOR THE ENZYMATIC REDUCTIVE CLEAVAGE OF GLYCOSIDIC BOND IN ANTHRACYCLINE ANTIBIOTICS

被引：50

作者：

KOMIYAMA, T ^{[1
]}

OKI, T ^{[1
]}

INUI, T ^{[1
]}

机构：

[1] SANRAKU OCEAN CO LTD,CENT RES LABS,FUJISAWA 251,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1979年 / 32卷 / 11期

关键词：

D O I：

10.7164/antibiotics.32.1219

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

[No abstract available]

引用

页码：1219 / 1222

页数：4

共 20 条

[1]

ASBELL MA, 1972, J PHARMACOL EXP THER, V182, P63

[2] NADPH CYTOCHROME-P-450 REDUCTASE ACTIVATION OF QUINONE ANTI-CANCER AGENTS TO FREE-RADICALS [J].

BACHUR, NR ;

GORDON, SL ;

GEE, MV ;

KON, H .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1979, 76 (02) :954-957

[3]

BACHUR NR, 1976, J PHARMACOL EXP THER, V197, P681

[4]

BENEDICT WF, 1977, CANCER RES, V37, P2209

[5]

ERNSTER L, 1967, METHOD ENZYMOL, V10, P309, DOI DOI 10.1016/0076-6879(67)10059-1

[6] GENERATION OF FREE-RADICALS AND LIPID PEROXIDATION BY REDOX CYCLING OF ADRIAMYCIN AND DAUNOMYCIN [J].

GOODMAN, J ;

HOCHSTEIN, P .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1977, 77 (02) :797-803

[7]

HANDA K, 1976, GANN, V67, P523

[8] ONE-ELECTRON-TRANSFER REACTIONS IN BIOCHEMICAL SYSTEMS .3. ONE-ELECTRON REDUCTION OF QUINONES BY MICROSOMAL FLAVIN ENZYMES [J].

IYANAGI, T ;

YAMAZAKI, I .

BIOCHIMICA ET BIOPHYSICA ACTA, 1969, 172 (03) :370-&

[9] ONE-ELECTRON-TRANSFER REACTIONS IN BIOCHEMICAL SYSTEMS .5. DIFFERENCE IN MECHANISM OF QUINONE REDUCTION BY NADH DEHYDROGENASE AND NAD(P)H DEHYDROGENASE (DT-DIAPHORASE) [J].

IYANAGI, T ;

YAMAZAKI, I .

BIOCHIMICA ET BIOPHYSICA ACTA, 1970, 216 (02) :282-&

[10]

KOMIYAMA T, GANN

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