DETERMINANTS OF DISEASE AND DISABILITY IN THE ELDERLY - THE ROTTERDAM ELDERLY STUDY

被引：993
作者：
HOFMAN, A
GROBBEE, DE
DEJONG, PTVM
VANDENOUWELAND, FA
机构：
[1] Department of Epidemiology and Biostatistics and Department of Ophthalmology, Erasmus University Medical School, DR Rotterdam, 3000
来源：
EUROPEAN JOURNAL OF EPIDEMIOLOGY | 1991年 / 7卷 / 04期
关键词：
AGING; COHORT STUDY; DETERMINANTS; DISEASE; EPIDEMIOLOGY; FOLLOW-UP STUDY;
D O I：
10.1007/BF00145007
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
In this paper the Rotterdam Elderly Study is presented. The aim of the study is to investigate determinants of disease occurrence and progression in the elderly. In addition to contributing to our understanding of the etiology of geriatric illnesses, the study is expected to lead to specific recommendations for intervention. The study focusses on causally related determinants of major diseases in the elderly. Fields of interest for the Rotterdam Elderly Study are conditions which interfere the most with the quality of life for the elderly. The aims of the Rotterdam Elderly Study are: (1) To investigate, by means of epidemiologic, clinical and basic research, the determinants of diseases in order to assess their etiologic significance. (2) To investigate potentially modifiable determinants in order to be able to develop preventive strategies by providing specific recommendations for intervention studies. The Rotterdam Elderly Study focusses on four primary areas of research: neurogeriatric diseases, cardiovascular diseases, locomotor diseases and ophthalmologic diseases. It is a prospective follow-up study, in which determinants of disease and determinants of progression of disease will be investigated in the total population of 55 years or over of the district of Ommoord in Rotterdam. It is anticipated that about 10,000 people will participate in the study and they will be examined in the period of 1991 to 1995.
引用
收藏
页码：403 / 422
页数：20
相关论文
共 95 条
  • [1] Aclimandos W.A., Galloway N.R., Blindness in the City of Nottingham (1980–1985), Eye, 2, pp. 431-434, (1988)
  • [2] Amaducci L.A., Fratiglioni L., Rocca W.A., Et al., Risk factors for clinically diagnosed Alzheimer's disease: a case-control study of an Italian population, Neurology, 36, pp. 922-31, (1986)
  • [3] A randomized controlled trial of aspirin in persons recovered from myocardial infarction, JAMA, 243, pp. 661-9, (1980)
  • [4] van Berkum F.N.R., Birkenhdger J.C., van Veen L.C.P., Noninvasive axial and peripheral assessment of bone mineral content: A comparison between osteoporotic women and normal subjects, J Bone Min Res, 4, pp. 679-85, (1989)
  • [5] Binswanger O., Die Begrenzung der allgememen progessiven Paralysie, Berl Klin Wochenschr, 31, pp. 1103-5, (1894)
  • [6] Boyce W.J., Vessey M.P., Rising incidence of fracture of the proximal femur, Lancet, 1, pp. 150-151, (1985)
  • [7] Briet E., Engesser L., Brommer E.J.P., Broekmans A.W., Bertina R.M., Thrombophilia: its causes and a rough estimate of its prevalence, Thromb Haemost, 58, pp. 39-43, (1987)
  • [8] Canner P.L., Aspirin in coronary heart disease. Comparison of six clinical trials, Isr J Med Sci, 19, pp. 413-23, (1983)
  • [9] Cobb S., The frequency of rheumatic diseases, (1971)
  • [10] Consensus development conference: prophylaxis and treatment of osteoporosis, Br Med J, 295, pp. 914-1915, (1987)
12345678910