CHANNEL-TYPE MOLECULAR-STRUCTURES .2. SYNTHESIS OF BOUQUET-SHAPED MOLECULES BASED ON A BETA-CYCLODEXTRIN CORE

被引：61

作者：

CANCEILL, J ^{[1
]}

JULLIEN, L ^{[1
]}

LACOMBE, L ^{[1
]}

LEHN, JM ^{[1
]}

机构：

[1] COLL FRANCE,CHIM INTERACT MOLEC LAB,11 PL MARCELIN BERTHELOT,F-75005 PARIS,FRANCE

来源：

HELVETICA CHIMICA ACTA | 1992年 / 75卷 / 03期

关键词：

D O I：

10.1002/hlca.19920750315

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new series of channel-type molecules presenting the features of potential transmembrane structures is described. They result from the grafting of amphiphilic side chains on a beta-cyclodextrin derivative 3 that constitutes the organizing core. They belong to the 'bouquet' family (B). Compounds bearing poly(oxyethylene) side chains, B(CD)O 16 and 17, and their polymethylene analogues B(CD)C 18 and 19, were synthesized. The properties investigated emphasize the suitability of such molecules to be incorporated into lipid bilayer membranes.

引用

页码：791 / 812

页数：22

共 22 条

[1]

Bender M. L., 1978, CYCLODEXTRIN CHEM, DOI [10.1007/978-3-642-66842-5, DOI 10.1007/978-3-642-66842-5]

[2]

BERGERON R, 1975, J BIOL CHEM, V250, P1223

[3] SELECTIVE ALKYLATION OF CYCLOHEPTAAMYLOSE [J].

BERGERON, RJ ;

MEELEY, MP ;

MACHIDA, Y .

BIOORGANIC CHEMISTRY, 1976, 5 (01) :121-126

[4] CYCLODEXTRIN CHEMISTRY - SELECTIVE MODIFICATION OF ALL PRIMARY HYDROXYL-GROUPS OF ALPHA-CYCLODEXTRINS AND BETA-CYCLODEXTRINS [J].

BOGER, J ;

CORCORAN, RJ ;

LEHN, JM .

HELVETICA CHIMICA ACTA, 1978, 61 (06) :2190-2218

[5]

BREITMAIER E, 1987, CARBON 13 NMR SPECTR, P163

[6] SYNTHESIS OF CHEMICALLY MODIFIED CYCLODEXTRINS [J].

CROFT, AP ;

BARTSCH, RA .

TETRAHEDRON, 1983, 39 (09) :1417-1474

[7] MILD PALLADIUM (0)-CATALYZED DEPROTECTION OF ALLYL ESTERS - A USEFUL APPLICATION IN THE SYNTHESIS OF CARBAPENEMS AND OTHER BETA-LACTAM DERIVATIVES [J].

DEZIEL, R .

TETRAHEDRON LETTERS, 1987, 28 (38) :4371-4372

[8]

DIKHANOV NN, 1974, KHIM PHARM ZH, V8, P37

[9] THEORY OF NUCLEAR OVERHAUSER ENHANCEMENT AND C-13-H-1 DIPOLAR RELAXATION IN PROTON-DECOUPLED C-13 NMR-SPECTRA OF MACROMOLECULES [J].

DODDRELL, D ;

ALLERHAN.A ;

GLUSHKO, V .

JOURNAL OF CHEMICAL PHYSICS, 1972, 56 (07) :3683-&

[10] AN APPROACH TO CHANNEL TYPE MOLECULAR-STRUCTURES .1. SYNTHESIS OF BOUQUET-SHAPED MOLECULES BASED ON AN [18]-O6 POLYETHER MACROCYCLE [J].

JULLIEN, L ;

LEHN, JM .

JOURNAL OF INCLUSION PHENOMENA AND MOLECULAR RECOGNITION IN CHEMISTRY, 1992, 12 (1-4) :55-74

← 1 2 3 →