ALTERED PINEAL SEROTONIN BINDING IN SOME SUICIDES

被引:5
作者
SPARKS, DL
LITTLE, KY
机构
[1] UNIV N CAROLINA, SCH MED, DEPT PSYCHIAT, CB 7160, WING B, CHAPEL HILL, NC 27599 USA
[2] UNIV KENTUCKY, MED CTR, SANDERS BROWN RES CTR, LEXINGTON, KY 40536 USA
[3] UNIV KENTUCKY, MED CTR, DEPT PATHOL, LEXINGTON, KY 40536 USA
[4] UNIV KENTUCKY, MED CTR, DEPT NEUROL, LEXINGTON, KY 40536 USA
[5] KENTUCKY JUSTICE CABINET, MED EXAMINERS PROGRAM, LEXINGTON, KY 40536 USA
关键词
melatonin; receptors; serotonin; Suicide;
D O I
10.1016/0165-1781(90)90131-N
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Serotonergic abnormalities have been regularly reported in the brains of suicide victims. Because of evidence that pineal function is altered in depressed subjects and that serotonin-releasing axons may innervate the pineal, we assayed tritiated serotonin binding in a series of control and suicide pineals. High affinity binding was present, and there were apparent differences between some suicides and controls. © 1990.
引用
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页码:19 / 28
页数:10
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