GENERATION OF SUPEROXIDE RADICALS IN ALKALINE-SOLUTIONS OF HYDROGEN-PEROXIDE AND THE EFFECT OF SUPEROXIDE-DISMUTASE ON THIS SYSTEM

被引：25
作者：
SYMONYAN, MA
NALBANDYAN, RM
机构：
[1] Institute of Biochemistry, Academy of Sciences of the Armenian SSR, Yerevan
来源：
BIOCHIMICA ET BIOPHYSICA ACTA | 1979年 / 583卷 / 03期
关键词：
Hydrogen peroxide; Superoxide dismutase; Superoxide radical generation;
D O I：
10.1016/0304-4165(79)90452-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Superoxide radicals in high concentrations were generated from alkaline H2O2 without using catalysts or irradiation. The dependence of the intensity and parameters of the superoxide radical EPR spectrum on pH, temperature, viscosity and H2O2 concentration were studied. The observed changes are explained on the base of matrix effects. The addition of superoxide dismutase to alkaline H2O2 led initially to a drop in the EPR spectrum intensity, followed by an increase in the concentration of superoxide radicals. © 1979.
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页码：279 / 286
页数：8
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